Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Feb 13;23(2):620–677. doi: 10.1007/s12311-022-01506-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 7 — Schematic representation of the olivo-cortico-nuclear interconnectivity. Note that each module, apart from their interconnected parts, also connects to the rest of the brain by their output (double arrowheads). Also note that the cortical part of each module is formed by one or several stripes of either zebrin II + or zebrin II- Purkinje cells. The mediolateral order of the represented modules, indicated from left to right in the diagram, is based on the mediolateral position of the CN and is not related to the mediolateral position of the cortical components. For example, the cortical A2 modules are located lateral to the cortical B-module [see 138]. IntDL receives input from zebrin II-negative PCs of cortical module D0, which is interspersed between zebrin II ⁺ stripes D1 and D2 and receives its olivary input from a part of the principal olive (IOPdm). Different shades of yellow, blue, and purple refer to Med, Int, and Lat modules, respectively. The green module is related to the lateral vestibular nucleus (LV). Note that modules of the vestibulocerebellum, i.e., with cortical input form nodulus and flocculus, are not indicated in this scheme. Abbreviations. Inferior olive (IO) per module from left to right: cIOMa, group a of caudal medial accessory olive (cIOM); cIOMb, group b of cIOM; cIOMbe, group beta of cIOM; cIOMd, group d of cIOM; cIOMc, group c of cIOM; IODdf, dorsal fold of dorsal inferior olive (IOD); IODvf, ventral fold of IOD; iIOM, intermediate part of medial accessory olive (IOM); rIOM, rostral part of IOM; IODvf, ventral fold of IOD; IOPvf, ventral fold of principal olive (IOP); IOPdm, dorsomedial group of IOP; IOPdf, dorsal fold of IOP. CX-zone: sagittally oriented zones of Purkinje cells in the cerebellar cortex indicated by capital letters A to D followed by either a number or a lowercase ‘x’ and related to zebrin-positive or zebrin-negative stripes. Cerebellar nuclei (CN) from left to right: vMed, ventral part of medial cerebellar nucleus (Med); rMed, rostral part of Med; cMed, caudal part of Med; MedcDL, caudal part of dorsolateral protuberance of Med; MedrDL, rostral part of dorsolateral protuberance of Med; IntIC, interstitial cell groups; LV, lateral vestibular nucleus; IntA, anterior interposed nucleus; IntIC, interstitial cell groups; IntP, posterior interposed nucleus; IntA, anterior interposed nucleus; vLat, ventral part of lateral cerebellar nucleus (lat); IntDL, dorsolateral hump; dLat, dorsal part of the Lat. Based on [20, 72, 139]