Figure 7.

Distribution of ML detected genes’ normalized expression in serum samples across different patient groups. Pink and blue colors represent CD and UC patients, respectively. The pattern differentiation—crosshatch for an inactive endoscopic state and circles for a severe endoscopic state—reflects the severity of endoscopic conditions. The x-axis labels (‘Yes’ or ‘No’) distinguish between the presence or absence of clinical symptoms in patients, with ‘Yes’ indicating clinical symptoms and ‘No’ representing the absence of symptoms. The groups are: CD patients without clinical symptoms and either inactive (pink, crosshatch, n=20) or severe (pink, circle, n=15) endoscopic states, CD patients with clinical symptoms and severe endoscopic states (pink, circle, n=12), UC patients without clinical symptoms and either inactive (blue, crosshatch, n=20) or severe (blue, circle, n=13) endoscopic states, UC patients with clinical symptoms and severe endoscopic states (blue, circle, n=14) and the control group (green, n=17). The Wilcoxon test was used to assess statistical significance in the comparison between the severe endoscopic IBD groups and the control group.