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. 2024 Mar 19;14:6594. doi: 10.1038/s41598-024-57101-2

Table 7.

Analysis of people with different states of depression based on 24-h pH monitoring results (rank mean, N = 518).

Variables No depression (0–7 points, N = 297) Mild depression (8–10 points, N = 128) Moderate to severe depression (11–21 points, N = 93) P
Number of refluxes (pH < 4) 223.76 294.42 325.58  < 0.001
% Time spent in reflux 222.37 300.59 321.51  < 0.001
Number of long refluxes (T ≥ 5 min) 226.35 295.36 316.03  < 0.001
DeMeester score 222.14 299.70 323.47  < 0.001
Oesophageal acid exposure  < 0.001
 Physiological reflux 220 (74.07%) 51 (39.84%) 28 (30.11%)
 Pathological reflux 77 (25.93%) 77 (60.16%) 65 (69.89%)
Diagnostic subgroup  < 0.001
 Physiologic reflux 210 (70.71%) 43 (33.59%) 22 (23.66%)
 NERD 51 (17.17%) 56 (43.75%) 51 (54.84%)
 RE 36 (12.12%) 29 (22.66%) 20 (21.50%)

The results of the Kruskal–Wallis test are expressed as rank averages; NERD non-erosive reflux disease, RE reflux esophagitis.