Table 2.
Static and dynamic parameters related to the left and right striatum for each patient.
| Pt. # | Grade | Age (y) | Sex (M/F) | Tremor side | Mean activity 3 h p.i. (kBq/ml) | SBR | Model parameters by SRTM | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Calculated | By DaTQUANT | BPND | R1 | K2 | ||||||||||||
| Right | Left | Right | Left | Right | Left | Right | Left | Right | Left | Right | Left | |||||
| 1 | 2 | 76 | M | L | 7.8 | 9.0 | 1.67 | 2.07 | 1.15 | 1.56 | 1.82 | 1.86 | 1.25 | 1.19 | 0.046 | 0.069 |
| 2 | 3 | 59 | M | R | 14.0 | 11.8 | 6.80 | 5.61 | 3.08 | 2.69 | 6.55 | 6.85a | 1.43 | 1.24 | 0.042 | 0.028 |
| 3 | 3 | 74 | M | R | 11.8 | 11.8 | 3.97 | 3.95 | 2.47 | 2.38 | 3.88 | 3.76 | 1.10 | 1.23 | 0.054 | 0.058 |
| 4 | 3 | 77 | M | R | 15.5 | 12.3 | 5.15 | 3.88 | 4.04 | 3.23 | 5.14 | 3.66 | 1.38 | 1.35 | 0.064 | 0.061 |
| Median (min;max) | 75 (59;77) | 12.9 (7.8;15.5) | 11.8 (9.0;12.3) | 4.56 (1.67;6.80) | 3.92 (2.07;5.61) | 2.78 (1.15;4.40) | 2.54 (1.56;3.23) | 4.51 (1.82;6.55) | 3.71 (1.86;6.85) | 1.32 (1.10;1.43) | 1.24 (1.19;1.35) | 0.050 (0.042;0.064) | 0.060 (0.028;0.069) | |||
| Combined median (min;max) | 11.8 (7.8;15.5) | 3.96 (1.67;6.80) | 2.58 (1.15;4.04) | 3.82 (1.82;6.85) | 1.25 (1.10;1.43) | 0.056 (0.028;0.069) | ||||||||||
| 5 | 4 | 73 | M | L | 16.3 | 12.2 | 6.13 | 4.36 | 4.54 | 3.23 | 6.68 | 7.20a | 1.98 | 1.98 | 0.049 | 0.027 |
| 6 | 4 | 78 | F | R | 17.3 | 18.0 | 5.86 | 6.11 | 3.82 | 3.81 | 7.52 | 7.17 | 1.29 | 1.25 | 0.050 | 0.056 |
| 7 | 5 | 55 | M | N/A | 19.2 | 18.9 | 6.50 | 6.38 | 4.80 | 5.03 | 8.04 | 7.67 | 1.08 | 1.30 | 0.083 | 0.079 |
| 8 | 5 | 56 | M | L | 21.1 | 19.4 | 6.30 | 5.70 | 4.39 | 4.21 | 9.83 | 7.79 | 1.80 | 1.24 | 0.030 | 0.032 |
| 9 | 5 | 70 | F | L | 20.8 | 19.6 | 6.64 | 6.20 | 4.40 | 4.04 | 6.75 | 5.86 | 1.72 | 1.34 | 0.069 | 0.085 |
| 10 | 5 | 73 | M | L | 19.8 | 19.7 | 8.23 | 8.16 | 4.73 | 4.83 | 8.19 | 7.75 | 1.72 | 1.39 | 0.074 | 0.084 |
| 11 | 5 | 83 | M | N/A | 23.1 | 21.4 | 7.63 | 7.02 | 3.89 | 4.06 | 9.35 | 8.62 | 1.89 | 1.66 | 0.052 | 0.049 |
| 12 | 5 | 69 | M | R | 22.7 | 23.5 | 8.07 | 8.47 | 5.60 | 5.66 | 7.59 | 7.81 | 0.59 | 0.77 | 0.060 | 0.064 |
| 13 | 5 | 57 | F | N/A | 33.4 | 33.6 | 10.00 | 10.07 | 6.50 | 6.79 | 9.13 | 9.00 | 1.19 | 0.69 | 0.096 | 0.096 |
| Median (min;max) | 70 (55;83) | 20.8 (16.3;33.4) | 19.6 (12.2;33.6) | 6.64 (5.86;10.00) | 6.38 (4.36;10.07) | 4.54 (3.82;6.50) | 4.21 (3.23;6.79) | 8.04 (6.68;9.83) | 7.75 (7.17;9.00) | 1.72 (0.59;1.98) | 1.30 (0.77;1.98) | 0.060 (0.030;0.096) | 0.064 (0.027;0.096) | |||
| Combined median (min;max) | 19.8 (12.2;33.6) | 6.57 (4.36;10.07) | 4.47 (3.23;6.79) | 7.77 (6.68;9.83) | 1.32 (0.59;1.98) | 0.062 (0.027;0.096) | ||||||||||
| Median, all (min;max) | 73 (55;83) | 19.2 (7.8;33.4) | 18.9 (9.0;33.6) | 6.50 (1.67;10.00) | 6.11 (2.07;10.07) | 4.39 (1.15;6.50) | 4.04 (1.56;6.79) | 7.52 (1.82;9.83) | 7.20 (1.86;9.00) | 1.38 (0.59;1.98) | 1.25 (0.77;1.98) | 0.054 (0.030:0.096) | 0.061 (0.027;0.096) | |||
The table shows data for all the patients with their grade (according to Kahraman), sex (male/female), tremor side (right-sided or left-sided) and the values, for left and right striatum, of 3 h post-injection (p.i.) mean activity concentrations, specific binding ratio (SBR) (as calculated and as extracted from DaTQUANT), non-displaceable binding potential (BP), R1 and K2. Patients #1–4 were categorized as low-score (LS) and patients #5–13 were categorized as high-score (HS). Medians (min;max) are presented for data from both right and left striatum and their combined right + left data, for both LS and HS patients. A median (min;max) of all patients’ data from both the left and the right striatum is also presented.
N/A Not applicable.
aHad standard error rates more than 100%.