Table 2.
Design scheme | VLP carrier | N-terminal insert | MIR insert | C-terminal insert |
---|---|---|---|---|
RBHcAg_MIR-II_N-II | RBHcAg | NSELLSLINDMPITNDQKKLMSNN | GILANSELLSLINDMPITNDQKKLMSNNL | none |
RBHcAg_MIR-II_C-II | RBHcAg | none | GILANSELLSLINDMPITNDQKKLMSNNL | NSELLSLINDMPITNDQKKLMSNN |
RBHcAg_MIR-II_NC-II | RBHcAg | NSELLSLINDMPITNDQKKLMSNN | GILANSELLSLINDMPITNDQKKLMSNNL | NSELLSLINDMPITNDQKKLMSNN |
RBHcAg_MIR-II_NC-VIII | RBHcAg | EVNKIKSALLSTNKAVVSL | GILANSELLSLINDMPITNDQKKLMSNNL | EVNKIKSALLSTNKAVVSL |
The sequences highlighted in bold represent the linkers added to the ends of the epitope.