Figure 6.

Application to real-world AWI adsorption problem. A A representative micrograph of single-particle cryoEM of purified human ClC-1 protein after applying FFC8 (at CMC, 3 mmol/L). As can be compared with Fig. 1, adding surfactant effectively solved the protein aggregation and deformation problem. B Two orthogonal shaded surface views of the resultant cryoEM map at an overall resolution of 3.6 Å, enabling de novo atomic modeling of the membrane domain (blue) of the complex (Wang et al. 2019). The intracellular domain is shown in yellow, and the detergent belt is in semi-transparent gray