Fig. 5.

The underlying mechanism of obesity and hyperuricemia. (A) Protein-protein interaction (PPI) network obtained from STRING database and constructed by Cytoscape. Each node size and color depth are proportional to their node degree. Edge width is proportional to the edge betweenness. (B) Grouping of KEGG enrichment analysis of the 235 intersected targets of obesity leading to hyperuricemia. Functionally related groups partially overlap. KEGG pathway is represented as a node. The nodes of a group are labeled in the same color. Two groups share the nodes with two colors.