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Effect of selenium supplementation on TPOAb (IU/mL), stratified by thyroid hormone replacement therapy, in Hashimoto thyroiditis (n = 2358). Black rectangles represent SMD for each study; the size of the rectangle is proportional to the weight of the study for the pooled effect. Horizontal lines indicate CI. The black diamond summarizes the pooled SMD data. (1)/(2) Indicate cohorts 1 and 2 of the study.
