Development of NA in cats infected with selected FIV
isolates. Groups of two SPF cats were infected with isolates obtained
from animals with broadly (left panels) or poorly (right panels)
cross-reactive NA. At the times indicated, injected cats were examined
for anti-FIV enzyme-linked immunosorbent assay (ELISA) antibodies with
gradient-purified, disrupted whole M2 virus as the antigen (▪) and
for NA antibodies to the homologous virus (open columns) and to
selected heterologous isolates (filled columns: ▤, M2; ▪, M17; ░⃞,
M26; ▨, M45; ▧, M92); cross-reactive NA to M73 tested constantly
negative.