Table 2.

Evaluation of the IC₅₀ of Mn₃O₄ NPs and MA against parasites to MA and CC₅₀ of Mn₃O₄ NPs.

Drugs	Amastigote		Promastigote		Macrophage	aSI
	aIC50 ± SD (μg·mL−1)	P-value	IC50 ± SD (μg·mL−1)	P-value	CC50 (μg·mL−1)	(Selectivity index)
MA	68.37 ± 3.22	NR	211.36 ± 59.63	NR	411.28 ± 46.35	6.01
Mn3O4 NPs	83.22 ± 4.26	P < 0.001	267.37 ± 38.33	P < 0.001	876.38 ± 68.36	10.53
Mix	38.34 ± 5.28	P < 0.001	163.35 ± 28.35	P < 0.001	583.32 ± 71.22	15.21