Table 3.
Multivariable negative binomial regression model's effects. Seizures recurrence Incidence Rate Ratios (IRRs), 95% Confidence Intervals (CI), and p-values are provided. Independent variable was treatment group (patients who received only lacosamide vs patients who received only levetiracetam), while adjustment was made for sex, age, history of seizures, tumor site, and MGMT methylation. ASM = antiseizure medication.
| Seizures recurrences |
|||
|---|---|---|---|
| Predictors | IRR | 95%CI | p |
| ASM used: Lacosamide (vs Levetiracetam) | 2.66 | 1.45–4.90 | 0.002 |
| Sex: Female | 1.79 | 0.99–3.27 | 0.056 |
| Age | 1.01 | 0.99–1.04 | 0.362 |
| History of seizures: Yes | 1.11 | 0.63–1.95 | 0.721 |
| Tumor site (reference pre-central): | |||
| Post-central | 1.64 | 0.79–3.40 | 0.189 |
| Temporo-insular | 0.87 | 0.45–1.70 | 0.690 |
| Basal ganglia/midbrain/multicentric | 1.06 | 0.12–9.31 | 0.956 |
| MGMT methylation |
0.55 |
0.30–1.01 |
0.050 |
| Observations | 130 | ||