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(A) SRC‐1 knockout in MEF cells was confirmed by Western blot analysis. (B) SRC‐1 knockout in MEF cells markedly re‐duced MMP‐9 mRNA level. (C) Downregulation of SRC‐1 decreased the invasive ability of MEF cells. Images and quantitation of SRC‐1 transient knockdown and control cells penetrating through the matrigel‐coated membrane. ***p < 0.001, ****p < 0.0001.
