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. 2024 Mar 20;28(7):e18213. doi: 10.1111/jcmm.18213

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© 2024 The Authors. Journal of Cellular and Molecular Medicine published by Foundation for Cellular and Molecular Medicine and John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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The methylation levels of YARS1 DNA exhibit a significant decrease in bladder cancer compared to normal bladder samples. (A) A comparison was made between the DNA methylation levels of YARS1 in bladder cancer and normal bladder samples. (B) The DNA methylation levels of YARS1 were compared across different stages of bladder cancer. (C) The DNA methylation levels of YARS1 were compared across different N‐stages of bladder cancer. (D) The distribution of methylation probes related to YARS1 on the chromosomal level was analysed. (E) Detailed genomic information regarding YARS1 was provided. (F) The differential expression of methylation probes associated with YARS1 was examined between bladder cancer and normal bladder samples. (G) A correlation analysis was conducted between YARS1‐associated methylation probes and YARS1 expression in bladder cancer. ns = p < .05, *p < .05, **p < .01, ***p < .001.