Table 1. (A) Relative Amounts of Point Mutation Types Observed in the Genomes of Untreated Control, dC-Treated, and 5CldC-Treated MEFs; (B) Relative Amounts of C → T Substitution Mutations Observed in Each DNA Strand in the Genome of MEFs Treated with 5CldC.

(A) types of substitution mutations induced by 5CldC
substitution type	control (%)	dC (%)	5CldC (%)
Transitions
CG → TA	39.1	26.8	86.2
TA → CG	9.3	16.8	7.9
Transversion
CG → AT	30.0	28.3	4.1
CG → GC	8.0	10.2	0.5
TA → AT	5.4	9.0	0.9
TA → GC	8.2	8.8	0.5
total number of substitutions	100	100	100

(B) strand bias in 5CldC-treated MEFs
	coding strand	noncoding strand	ratio
number of C → T substitutions	60.9%	39.1%	1.56