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. 2022 Dec 28;75(3):352–363. doi: 10.1002/art.42353

Table 2.

Action potential properties of mouse DRG neurons isolated from mice in each group in in vitro studies*

Control NGF NGF plus MSC‐EV
(n = 23) (n = 23) (n = 20)
Diameter, μm 31.51 ± 1.01 30.93 ± 0.78 31.24 ± 0.95
Resting membrane potential, mV –51.78 ± 1.19 –45.48 ± 1.40 –49.9 ± 1.30
Threshold, pA 706.5 ± 48.22 568.2 ± 47.39§ 730 ± 54.34
Half peak duration, msec 1.67 ± 0.12 1.45 ± 0.13 1.98 ± 0.17
Afterhyperpolarization duration, msec 25.18 ± 2.77 17.39 ± 3.7 28.38 ± 3.25
Afterhyperpolarization amplitude, mV 17.33 ± 0.76 16.02 ± 0.96 17.39 ± 0.84
*

Values are the mean ± SEM. Each group included seeded dorsal root ganglion (DRG) neurons isolated from 4 mice. MSC‐EV = mesenchymal stem/stromal cell–derived extracellular vesicle.

P < 0.01 versus control neurons by one‐way analysis of variance (ANOVA) followed by Tukey's post hoc test.

P < 0.05 versus nerve growth factor (NGF)–treated neurons by one‐way ANOVA followed by Tukey's post hoc test.

§

P < 0.05 versus control neurons by one‐way ANOVA followed by Tukey's post hoc test.