Table 2.
Control | NGF | NGF plus MSC‐EV | |
---|---|---|---|
(n = 23) | (n = 23) | (n = 20) | |
Diameter, μm | 31.51 ± 1.01 | 30.93 ± 0.78 | 31.24 ± 0.95 |
Resting membrane potential, mV | –51.78 ± 1.19 | –45.48 ± 1.40† | –49.9 ± 1.30‡ |
Threshold, pA | 706.5 ± 48.22 | 568.2 ± 47.39§ | 730 ± 54.34‡ |
Half peak duration, msec | 1.67 ± 0.12 | 1.45 ± 0.13 | 1.98 ± 0.17‡ |
Afterhyperpolarization duration, msec | 25.18 ± 2.77 | 17.39 ± 3.7 | 28.38 ± 3.25 |
Afterhyperpolarization amplitude, mV | 17.33 ± 0.76 | 16.02 ± 0.96 | 17.39 ± 0.84 |
Values are the mean ± SEM. Each group included seeded dorsal root ganglion (DRG) neurons isolated from 4 mice. MSC‐EV = mesenchymal stem/stromal cell–derived extracellular vesicle.
P < 0.01 versus control neurons by one‐way analysis of variance (ANOVA) followed by Tukey's post hoc test.
P < 0.05 versus nerve growth factor (NGF)–treated neurons by one‐way ANOVA followed by Tukey's post hoc test.
P < 0.05 versus control neurons by one‐way ANOVA followed by Tukey's post hoc test.