Figure 4. Consequences of different percentage falls of cerebral blood flow.

Schematic representation based on patient studies of ageing humans; animal experiments with coils placed on arteries to the brain giving a 30% cerebral blood flow (CBF) fall; 2‐vessel occlusion experiments in rodents giving a ∼50% CBF fall; middle cerebral artery occlusion in rodents producing at least an ∼80% fall in CBF.