Fig. 3.

3D visualization of discontinuous B cell epitopes in H5N1 construct. Yellow regions are related to discontinuous amino acids in the final H5N1 construct. A Amino acids of F169, G170, P171, G172, P173, G174, P175, G176, P177, T178, T179, Y180, I181, S182, I183, G184, T185, S186, T187, L188, N189, Q190 and R191. B Amino acids of K315, K316, E317, A318, A319, A320, K321, A322, K323, F324, V325, A326, A327, W328, T329, L330, K331, A332, A333, A334, E335, A336, A337, A338, K339, E340, A341, A342, A343, K344, H346 and H347. C Amino acids of R209, T210, L211, D212, F213, H214, G215, P216, G217, P218, G219, P220, G221, N222, L223, Y224, D225, K226, V227, R228, L229, Q230, L231 and R232. DAmino acids of D233, N234, A235, K236, E237, E239, and Y240. E Amino acids of P78, L79, T80, I81, A82 and I85. F Amino acids of M250, R251, and Y254. G Amino acids of G241, A242, E243, A244, E246, and R247. H G161, L162, D163, C164, I165, and R166. (I)Amin acids of V291, L292, S293, C294, L295, P296, K297, S305, T306, R307, G308, and R309