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. 2024 Mar 20;23:82. doi: 10.1186/s12944-024-02074-4

Table 1.

Baseline characteristics of the gallstones group versus the no-gallstones group.

Characteristics Overall, N = 4,841 Gallstones, N = 413 No gallstones, N= 4,428 P value
Gender, n (%) <0.001
 Male 2,277 (47.04%) 101 (24.46%) 2,176 (49.14%)
 Female 2,564 (52.96%) 312 (75.54%) 2,252 (50.86%)
Age 44 (32, 58) 52 (39, 64) 43 (31, 57) <0.001
Race, n (%) <0.001
 Mexican American 632 (13.06%) 59 (14.29%) 573 (12.94%)
 Non-Hispanic White 1,664 (34.37%) 174 (42.13%) 1,490 (33.65%)
 Non-Hispanic Black 1,255 (25.92%) 81 (19.61%) 1,174 (26.51%)
 Other Races 1,290 (26.65%) 99 (23.97%) 1,191 (26.90%)
Education level, n (%) 0.823
 Grades 0–12 802 (16.57%) 72 (17.43%) 730 (16.49%)
 High school graduate/GED 1,172 (24.21%) 102 (24.70%) 1,070 (24.16%)
 Some college or above 2,867 (59.22%) 239 (57.87%) 2,628 (59.35%)
Marital status, n (%) <0.001
 Married/Living with Partner 2,788 (57.59%) 254 (61.50%) 2,534 (57.23%)
 Widowed/Divorced/Separated 903 (18.65%) 95 (23.00%) 808 (18.25%)
 Unmarried 1,150 (23.76%) 64 (15.50%) 1,086 (24.53%)
PIR, n (%) 0.495
 <2 1,944 (40.16%) 161 (38.98%) 1,783 (40.27%)
 ≥2 2,305 (47.61%) 207 (50.12%) 2,098 (47.38%)
 Unclear 592 (12.23%) 45 (10.90%) 547 (12.35%)
Hypertension, n (%) <0.001
 Yes 1,625 (33.57%) 199 (48.18%) 1,426 (32.20%)
 No 3,216 (66.43%) 214 (51.82%) 3,002 (67.80%)
Diabetes, n (%) <0.001
 Yes 468 (9.67%) 72 (17.43%) 396 (8.94%)
 No 4,373 (90.33%) 341 (82.57%) 4,032 (91.06%)
Fatty liver, n (%) <0.001
 No 2,962 (61.19%) 200 (48.43%) 2,762 (62.38%)
 Mild 699 (14.44%) 74 (17.92%) 625 (14.11%)
 Severe 1,180 (24.38%) 139 (33.66%) 1,041 (23.51%)
Smoking, n (%) 0.062
 Current smokers 952 (19.67%) 77 (18.64%) 875 (19.76%)
 Former smokers 958 (19.79%) 100 (24.21%) 858 (19.38%)
 Never smokers 2,931 (60.55%) 236 (57.14%) 2,695 (60.86%)
Alcohol consumption, n (%) 0.003
 Heavy 1,657 (34.23%) 109 (26.39%) 1,548 (34.96%)
 Moderate 483 (9.98%) 44 (10.65%) 439 (9.91%)
 Mild 843 (17.41%) 72 (17.43%) 771 (17.41%)
 Never 1,858 (38.38%) 188 (45.52%) 1,670 (37.71%)
BMI (kg/m2) 28 (24, 33) 32 (27, 38) 28 (24, 33) <0.001
TG (mmol/L) 1.19 (0.84, 1.73) 1.34 (0.95, 1.82) 1.16 (0.84, 1.72) <0.001
HDL-C (mmol/L) 1.32 (1.11, 1.60) 1.32 (1.11, 1.58) 1.32 (1.09, 1.63) 0.626
TC (mmol/L) 4.76 (4.16, 5.43) 4.76 (4.19, 5.43) 4.76 (4.16, 5.43) 0.689
ALT (U/L) 17 (13, 25) 17 (13, 25) 17 (13, 25) 0.837
AST (U/L) 19 (16, 24) 19 (15, 23) 19 (16, 24) 0.064
GGT(IU/L) 20 (14, 31) 20 (15, 33) 20 (14, 31) 0.255
Protein intake (g) 73 (55, 97) 64 (49, 85) 74 (55, 98) <0.001
Carbohydrate intake (g) 225 (167, 301) 214 (154, 279) 226 (168, 303) 0.002
Fat intake (g) 77 (55, 107) 71 (53, 99) 78 (55, 107) 0.006
Water intake (g) 2,558 (1,889, 3,408) 2,415 (1,790, 3,313) 2,567 (1,896, 3,414) 0.046
Magnesium intake(mg) 275 (201, 376) 260 (184, 345) 277 (202, 379) <0.001
Calcium intake(mg) 799 (554, 1,116) 793 (536, 1,052) 801 (555, 1,121) 0.205
Iron intake(mg) 12 (9, 16) 11 (8, 15) 12 (9, 17) <0.001
Zinc intake(mg) 9.2 (6.7, 12.7) 8.2 (6.1, 11.4) 9.3 (6.7, 12.8) <0.001
AIP -0.06 (-0.26, 0.16) -0.01 (-0.19, 0.20) -0.06 (-0.27, 0.16) <0.001

Median (IQR) for continuous variables; N (%) for categorical variables

Abbreviations: PIR Ratio of household income to poverty, GED General equivalency diploma, BMI Body mass index, TG Triglyceride, HDL-C High density lipoprotein cholesterol, TC Total cholesterol, ALT Alanine Aminotransferase, AST Aspartate Aminotransferase, GGT Gamma Glutamyl Transferase; AIP Atherogenic index of plasma