FIGURE 3.

Cigarette smoke (CS)‐induced loss of lean mass and systemic lymphocytosis were prevented by apocynin treatment. Mice were exposed to CS or room air (sham) for 8 weeks with i.p. injection of apocynin (5 mg·kg⁻¹·day⁻¹) or vehicle (saline). Change in body weight (a), alterations in body lean (b) and fat (c) mass. Haematology analysis of total white blood cells (d), mid‐range cells (e), granulocytes (f) and lymphocytes (g). Data are expressed as mean + SEM (n = 8 mice per group) and analysed by two‐way ANOVA with multiple comparisons and Tukey post hoc test. *P < 0.05, denotes differences between the compared groups.