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. 2023 Mar 30;62(25):e202215785. doi: 10.1002/anie.202215785

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© 2023 The Authors. Angewandte Chemie International Edition published by Wiley-VCH GmbH

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Composition and structures of the lipid bilayer. (A) Chart showing approximated proportions of key lipid components of neuronal membranes by weight. ^[62] PC=Phosphatidylcholine; PE=phosphatidylethanolamine; PS=phosphatidylserine; GM=ganglioside; SM=sphingomyelin. (B) Some key phospholipid headgroups. (C) Cholesterol structure. (D) Two of many acyl chain combinations, 16:0–18 : 1 PS (POPS) 1‐palmitoyl‐2‐oleoyl‐sn‐glycero‐3‐phospho‐L‐serine; 18 : 1–18 : 1 (DOPC) 1,2‐Dioleoyl‐sn‐glycero‐3‐phosphocholine. (E) Cartoon of membrane structures.