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Membrane permeability to Ca2+ ions in vesicles and cellular systems. (A) Fibril formation monitored alongside Ca2+ influx into lipid vesical. Direct relationship between prefibrillar Aβ42 oligomer levels and Ca2+ influx. [119a] (B) Ca2+ influx into cells detected by Fluro‐2 only observed for Aβ oligomers added to the extracellular culture. The average of 22 individual cell recordings is shown in the lower trace. [121]
