FIGURE 10.

Schematic summary of main fiber‐ and cytoarchitectural, immunohistochemical, and genetic identifying features, proposed to provide standardized criteria to define and delineate the claustrum complex (CLCX) and its individual subdivisions. As can be seen, the dCL is genetically different from the three remaining subregions and can be delineated by the presence of diagonally oriented myelin basic protein (MBP) fibers and cellular architecture. In contrast, vCl has a dense expression of genetic markers like Nr2f2 and Rxfp1 and can be identified in experimental material by the unique clustering of cell bodies in an area that lacks MBP and calbindin (CB) labeling. The mDEn is uniquely labeled by markers that co‐express in the cortical subplate, like Cplx3, Ctgf, and Galnt10, and shows a striped pattern in both MBP labeling and cellular organization in addition to a complete absence of parvalbumin (PV) labeling. Lastly, the lDEn is genetically populated by the same markers that express in the vCL in addition to the Npsr1 gene and can be delineated by a dense population of CB labeled cells or a sparser PV plexus, and by its dense cell packing relative to the mDEn and piriform cortex.