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. 2024 Jan 8;11(11):2306788. doi: 10.1002/advs.202306788

Figure 3.

Figure 3

AAV‐OTOF was audiologically and systemically safe in cynomolgus macaques. A) The experimental procedure in cynomolgus macaques. B) The images of round window membrane exposure and AAV injection in cynomolgus macaques. C) The ABR results of click and tone‐burst in cynomolgus macaques injected with menstruum, low dose AAV‐OTOF, and high dose AAV‐OTOF, respectively. I: ipsilateral ear, C: contralateral ear. D) The HE staining of tissues from control and AAV‐OTOF injected cynomolgus macaques. Scale bar: 100 µm.