Table 3. Poisson regression analysis with robust variance for comorbidities associated with in-hospital mortality in patients with COVID-19 admitted to hospitalization in Lima, Peru. March to October 2020.
| Comorbidities | Crude model | Adjusted model a | ||||
|---|---|---|---|---|---|---|
| RR | 95% CI | p-value | RR | 95% CI | p-value | |
| Age 18-29 years (n=2366) | ||||||
| Obesity | 1.53 | 0.88-2.63 | 0.130 | 0.75 | 0.45-1.26 | 0.282 |
| Diabetes | 2.41 | 1.16-4.99 | 0.018 | 1.46 | 0.72-2.96 | 0.296 |
| Cardiovascular disease | 4.74 | 2.86-7.85 | <0.001 | 2.16 | 1.24-3.74 | 0.006 |
| Chronic neurological disease | 6.07 | 3.39-10.85 | <0.001 | 5.03 | 2.60-9.74 | <0.001 |
| Renal disease | 6.50 | 4.15-10.17 | <0.001 | 5.01 | 2.88-8.71 | <0.001 |
| Chronic lung disease | 1.48 | 0.40-5.46 | 0.553 | 0.86 | 0.31-2.40 | 0.777 |
| Asthma | 1.15 | 0.39-3.39 | 0.804 | 0.51 | 0.24-1.10 | 0.087 |
| Liver disease | 3.97 | 1.27-12.42 | 0.018 | 3.82 | 1.16-12.55 | 0.027 |
| Immunodeficiency | 1.48 | 0.24-9.31 | 0.675 | 1.02 | 0.16-6.61 | 0.986 |
| Cancer | 9.12 | 6.53-12.74 | <0.001 | 7.29 | 4.56-11.64 | <0.001 |
| Age 30-59 years (n=23,781) | ||||||
| Obesity | 1.51 | 1.41-1.61 | <0.001 | 1.30 | 1.22-1.39 | <0.001 |
| Diabetes | 1.32 | 1.24-1.41 | <0.001 | 1.12 | 1.06-1.20 | <0.001 |
| Cardiovascular disease | 1.36 | 1.27-1.45 | <0.001 | 1.14 | 1.07-1.21 | <0.001 |
| Chronic neurological disease | 1.53 | 1.25-1.87 | <0.001 | 1.36 | 1.12-1.65 | 0.002 |
| Kidney disease | 2.03 | 1.84-2.25 | <0.001 | 1.87 | 1.68-2.09 | <0.001 |
| Chronic lung disease | 1.46 | 1.25-1.71 | <0.001 | 1.30 | 1.11-1.51 | 0.001 |
| Asthma | 0.88 | 0.73-1.06 | 0.188 | 0.92 | 0.77-1.10 | 0.378 |
| Liver disease | 1.66 | 1.32-2.09 | <0.001 | 1.55 | 1.21-1.99 | 0.001 |
| Immunodeficiency | 2.00 | 1.67-2.41 | <0.001 | 2.18 | 1.77-2.69 | <0.001 |
| Cancer | 2.17 | 1.94-2.42 | <0.001 | 2.38 | 2.10-2.70 | <0.001 |
| Age >60 years (n=25,356) | ||||||
| Obesity | 1.06 | 1.01-1.11 | 0.011 | 1.12 | 1.07-1.17 | <0.001 |
| Diabetes | 0.99 | 0.97-1.02 | 0.672 | 1.00 | 0.98-1.03 | 0.859 |
| Cardiovascular disease | 1.05 | 1.02-1.07 | <0.001 | 0.99 | 0.96-1.01 | 0.179 |
| Chronic neurological disease | 1.19 | 1.13-1.26 | <0.001 | 1.10 | 1.03-1.16 | 0.002 |
| Kidney disease | 1.17 | 1.12-1.22 | <0.001 | 1.10 | 1.06-1.15 | <0.001 |
| Chronic lung disease | 1.18 | 1.12-1.24 | <0.001 | 1.13 | 1.07-1.18 | <0.001 |
| Asthma | 0.95 | 0.86-1.05 | 0.296 | 0.98 | 0.89-1.07 | 0.613 |
| Liver disease | 1.16 | 1.07-1.27 | 0.001 | 1.20 | 1.10-1.31 | <0.001 |
| Immunodeficiency | 1.08 | 0.90-1.30 | 0.427 | 1.14 | 0.96-1.37 | 0.144 |
| Cancer | 1.21 | 1.15-1.27 | <0.001 | 1.23 | 1.17-1.29 | <0.001 |
a
Adjusted for age, sex in years, being health personnel, admission to intensive care, need for mechanical ventilation, type of health facility and the period in which the case was reported. RR: relative risk, 95% CI: 95% confidence interval.