Table 3.
Results from Three Aalen's linear Hazard models (Beta Coefficients (excess number of cases per 10,000 person years) and 95% CIs With the Latter Two Including Educational Attainment First as a Main Effect and then in Two and Three-Way Interactions*
| AUD | DUD | |||
|---|---|---|---|---|
| Beta Coefficient | Z-value | Beta Coefficient | Z-value | |
| Model A | ||||
| FGRS | 4.25 (2.16; 3.34) | 70.5 | 3.58 (3.50; 3.66) | 67.2 |
| GAEA | −1.64 (−1.70; −1.58) | 41.3 | −1.67 (−1.72; −1.62) | 48.5 |
| Year of Birth | 0.13 (0.12; 0.14) | 15.1 | 0.23 (0.22; 0.23) | 26.5 |
| Male vs Female | 5.81 (5.69; 5.93) | 49.7 | 2.89 (2.79; 2.99) | 30.4 |
| FGRS * GAEA | −1.06 (−1.14; −0.98) | 24.8 | −1.24 (−1.32; −1.16) | 28.3 |
| Model B | ||||
| FGRS | 4.08 (3.99; 4.17) | 68.4 | 3.45 (3.37; 3.53) | 66.3 |
| GAEA | −0.41 (−0.47; −0.41) | 10.8 | −0.36 (−0.41; −0.31) | 11.3 |
| Year of Birth | 0.13 (0.12; 0.14) | 14.4 | 0.23 (0.22; 0.24) | 25.1 |
| Male vs Female | 5.81 (5.69; 5.93) | 46.0 | 2.87 (2.77; 2.97) | 27.8 |
| FGRS * GAEA | −1.04 (−1.12; −0.96) | 24.4 | −1.22 (−1.30; −1.14) | 28.3 |
| EA | −2.93 (−2.99; −2.87) | 61.3 | −3.08 (−3.14; −3.02) | 64.0 |
| Model C | ||||
| FGRS | 3.80 (3.71; 3.89) | 61.1 | 2.97 (2.88; 3.06) | 57.3 |
| GAEA | −0.52 (−0.59; −0.45) | 12.6 | −0.53 (−0.59; −0.47) | 14.5 |
| Year of Birth | 0.13 (0.12; 0.14) | 14.1 | 0.22 (0.21; 0.23) | 24.8 |
| Male vs Female | 5.81 (5.69; 5.93) | 46.6 | 2.87 (2.77; 2.97) | 28.5 |
| FGRS * GAEA | −0.39 (−0.48; −0.30) | 8.2 | −0.39 (−0.48; −0.30) | 8.4 |
| EA | −2.99 (−3.06; −2.92) | 60.0 | −3.12 (−3.18; −3.06) | 63.4 |
| FGRS* EA | −1.61 (−1.71; −1.51) | 30.4 | −2.01 (−2.11; −1.91) | 39.6 |
| GAEA * EA | 0.57 (0.51; 0.63) | 18.1 | 0.80 (0.74; 0.85) | 28.0 |
| FGRS* GAEA*EA | 0.30 (0.22; 0.38) | 7.3 | 0.50 (0.42; 0.58) | 11.9 |
FGRS = Familial genetic Risk Score; GAEA = Genetic Aptitude for Educational Attainment; EA = Educational Attainment; Cases with registrations prior to age 25 are excluded (NAUD = 31,851 (31.8%); NDUD = 12,516 (19.9%))