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CYP2C19 allele dependent enzyme activity
| CYP2C19 allele | Enzyme activity | Homozygous | Heterozygous (with *1 or *17) |
|---|---|---|---|
| *1 | Normal | EM | UM |
| *2 | None | PM | IM |
| *3 | None | PM | IM |
| *4 | None | PM | IM |
| *5 | None | PM | IM |
| *6 | None | PM | IM |
| *7 | None | PM | IM |
| *8 | None | PM | IM |
| *9 | Decreased | PM | IM |
| *10 | Decreased | PM | IM |
| *17 | Increased | UM | UM |
Abbreviations: EM, extensive metaboliser; IM, intermediate metaboliser; PM, poor metaboliser; UM, ultrarapid metaboliser.
