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. 2024 Mar 20;7(3):e2038. doi: 10.1002/cnr2.2038

TABLE 2.

HRQoL among patients with gastrointestinal cancer.

Questionnaire Scale/item Esophageal cancer patients (n = 160) Gastric cancer patients (n = 103) Colorectal cancer patients (n = 96)
Mean ± SEM Mean ± SEM Mean ± SEM

EORTC QLQ‐C30

Global health status 47.0 ± 1.5 50.7 ± 1.6 48.9 ± 1.9
Functional scales
Cognitive functioning 78.0 ± 1.9 85.4 ± 1.9 83.0 ± 2.0
Physical functioning 62.0 ± 1.7 57.2 ± 2.1 65.9 ± 2.0
Emotional functioning 52.6 ± 2.6 62.5 ± 3.5 52.9 ± 3.4
Role functioning 46.5 ± 2.5 37.1 ± 3.0 58.5 ± 3.0
Social functioning 28.3 ± 2.1 36.6. ±2.9 44.1 ± 2.8
Symptom scales/items
Financial difficulties 79.4 ± 2.1 81.2 ± 2.7 70.1 ± 2.9
Appetite loss 51.3 ± 2.7 50.8 ± 3.2 42.4 ± 3.6
Fatigue 50.9 ± 2.0 53.4 ± 2.2 47.9 ± 2.7
Pain 49.1 ± 2.4 52.1 ± 2.9 31.8 ± 2.7
Nausea and vomiting 33.2 ± 2.4 29.9 ± 2.9 22.4 ± 2.3
Constipation 20.3 ± 2.3 16.2 ± 2.4 13.5 ± 2.3
Diarrhea 20.0 ± 2.3 16.5 ± 2.3 16.0 ± 2.5
Insomnia 18.1 ± 2.0 14.9 ± 2.4 25.7 ± 3.1
Dyspnoea 14.0 ± 1.8 18.4 ± 3.1 16.3 ± 2.7

EORTC QLQ‐ OES18

Symptom scales/items
Dysphagia 72.2 ± 1.7
Trouble with taste 55.8 ± 2.6
Reflux 47.3 ± 2.2
Trouble swallowing saliva 31.7 ± 2.7
Eating 33.1 ± 1.8
Dry mouth 29.2 ± 2.6
Trouble with coughing 24.6 ± 2.5
Pain 23.9 ± 1.7
Choked when swallowing 23.5 ± 2.3
Trouble talking 19.8 ± 2.0
EORTC QLQ‐ STO22 Symptom scales/items
Taste 67.3 ± 3.3
Anxiety 56.2 ± 3.1
Reflux 55.9 ± 2.6
Pain 50.4 ± 2.5
Eating 47.7 ± 2.8
Body image 34.0 ± 3.5
Dysphagia 22.1 ± 2.2
Dry mouth 21.7 ± 3.1
Hair loss 6.8 ± 1.9
EORTC QLQ‐CR29 Functional scales
Sexual interest (women) 92.3 ± 2.4
Sexual interest (men) 78.1 ± 6.3
Body image 66.8 ± 2.9
Weight 58.0 ± 3.6
Anxiety 41.0 ± 3.5
Symptom scales/items
Taste 40.0 ± 3.1
Bloating 39.2 ± 3.2
Flatulence 34.0 ± 2.8
Abdominal pain 31.9 ± 2.7
Sore skin 30.6 ± 2.9
Urinary frequency 30.2 ± 2.3
Stool frequency 24.1 ± 1.9
Buttock pain 21.9 ± 2.9
Dry mouth 20.1 ± 2.8
Blood and mucus in stool 18.2 ± 2.4
Fecal incontinence 16.0 ± 2.5
Embarrassment 15.3 ± 2.6
Dysuria 13.5 ± 1.9
Hair loss 12.8 ± 2.1
Stoma care problems 5.6 ± 1.7
Urinary incontinence 4.5 ± 1.2
Impotence 3.8 ± 1.4
Dyspareunia 1.0 ± 0.6

Note: EORTC QLQ 30: European Organisation for Research and Treatment of Cancer quality of life questionnaire, EORTC QLQ‐OES18: European Organisation for Research and Treatment of Cancer quality of life questionnaire for esophageal Cancer, SEM: Standard error of the mean. EORTC QLQ‐STO22: European Organisation for Research and Treatment of Cancer quality of life questionnaire for gastric Cancer. EORTC QLQ‐CR29: European Organisation for Research and Treatment of Cancer quality of life questionnaire for Colorectal Cancer.