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Diagrammatic representation of the envelope of FIV.
Sites of proteolytic cleavage eliminating an amino-terminal signal
peptide (arrowhead) and generating mature surface (SU) and
transmembrane (TM) envelope glycoproteins (arrow) are indicated.
Peptides SU2, SU5, and TM3 were used as immunogens. Positions
correspond to the amino acid sequence of the envelope glycoprotein of
the Wo strain. Symbols: ▪, peptides;
, signal sequence;
, putative
membrane-spanning domain.
