TABLE 3.
Plasma viremia 3 weeks after infection
| Group and cats no. | Plasma viremia by:
|
|
|---|---|---|
| RT-PCRa | PBMC cultureb | |
| TM3c | ||
| 346d | <1.43 × 104 | 1 |
| 347 | 1.19 × 107 | 1 × 102 |
| 348d | <1.43 × 104 | 1 |
| 349 | 5.56 × 106 | 1 |
| Adjuvant | ||
| 354 | 1.93 × 108 | 5 × 103 |
| 355 | 2.43 × 108 | 5 × 102 |
| 356 | 3.12 × 107 | 5 × 103 |
| 357 | 2.54 × 109 | 5 × 104 |
a
Plasma viremia as measured by competitive RT-PCR and expressed as the number of copies of viral RNA per milliliter of plasma.
b
Plasma viremia as measured by PBMC culture and expressed as TCID50 per milliliter of plasma.
c
The reduction in viral burden in the TM3 group was statistically significant whether RNA copy number (P = 0.02) or infectious titer (P = 0.017) was considered.
d
Since no viral RNA was detected at 3 weeks by RT-PCR for cats 346 and 348, the estimated threshold of detection for these samples is indicated (see the legend to Fig. 3).