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. 2023 Oct 26;78(3):702–710. doi: 10.1093/cid/ciad656

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© The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — DTG trough concentrations in infants with a human immunodeficiency virus (HIV) viral load >1000 copies/mL on study day 180 versus those with an HIV viral load <1000 copies/mL. Squares represent infants receiving DTG twice-daily dosing with rifampicin; circles indicate infants receiving DTG once-daily dosing without rifampicin. Abbreviations: C_trough, trough concentration; DTG, dolutegravir; EC₉₀, 90% effective concentration; IC₉₀, in vitro protein-adjusted 90% maximal inhibitory concentration.