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Paul Berg and DTD1. (A) Schematics showing the two chiral forms of amino acid, i.e. l- and d-amino acid, in addition to achiral glycine that are ligated to transfer RNA by aminoacyl-tRNA synthetases. (B) Table (Adapted from Calendar R., Berg P., JMB, 1967) and schematics showing the biochemical activity of d-aminoacyl-tRNA deacylase1 (DTD1) from bacteria on l- and d-aminoacyl-tRNAs and glycyl-tRNA originally observed by Calendar and Berg (17) (Here tRNA is referred to as RNA).
