Table 4.
High PM2.5 exposure was associated with a priori HMOs.
| β | P Value | |
|---|---|---|
| HMO summary measures | ||
| Diversity | − 0.82 | 0.002 |
| Sum (nmol/mL) | 788.70 | 0.002 |
| HMO-bound sialic acid (nmol/mL) | 24.82 | 0.83 |
| HMO-bound fucose (nmol/mL) | 485.25 | 0.08 |
| HMO concentrations | ||
| 2’FL (nmol/mL) | 899.63 | 0.05 |
| 6’SL (nmol/mL) | 61.71 | 0.20 |
| DSLNT (nmol/mL) | 3.75 | 0.89 |
| 3FL (nmol/mL) | 763.23 | 0.0001 |
| LNT (nmol/mL) | − 48.53 | 0.59 |
| LNnT (nmol/mL) | − 53.24 | 0.24 |
Effect estimates (β) and unadjusted p values from the multivariate linear regression models are shown where PM2.5 was treated as a categorical variable (high/low). Multivariable models adjusted for maternal age and socioeconomic status. Unadjusted P-values less than 0.05 are denoted in bold text.