Table 8.
Ambient air pollution exposure was associated with breastmilk HMOs.
NO2 | PM10 | PM2.5 | |||||||
---|---|---|---|---|---|---|---|---|---|
β | P Value | PFDR | β | P Value | PFDR | β | P Value | PFDR | |
LNFP I (nmol/mL) | 105.47 | 0.23 | 0.43 | − 36.10 | 0.68 | 0.74 | − 178.41 | 0.041 | 0.22 |
LNFP II (nmol/mL) | − 83.34 | 0.0045 | 0.17 | − 68.33 | 0.021 | 0.17 | − 70.27 | 0.017 | 0.17 |
DFLNT (nmol/mL) | − 74.56 | 0.18 | 0.38 | − 119.02 | 0.032 | 0.21 | − 145.13 | 0.008 | 0.17 |
LNH (nmol/mL) | − 2.42 | 0.61 | 0.69 | 6.43 | 0.18 | 0.38 | 9.38 | 0.047 | 0.22 |
FLNH (nmol/mL) | − 8.28 | 0.33 | 0.52 | 14.58 | 0.09 | 0.24 | 19.47 | 0.021 | 0.17 |
Multivariable models adjusted for maternal age and socioeconomic status. Unadjusted P-values less than 0.05 are denoted in bold text. The table also includes the adjusted (PFDR) p-values from the exploratory analysis. All effect estimates (β) are reported for a one standard deviation increase in NO2 (SD: 2.23 ppb), PM10 (SD: 3.65 µg/), and PM2.5 exposure (SD: 1.02 µg/).