Table 1.

MR results of causal effects between gut microbiota and EFMR (main).

Disease type (outcome)	Gut microbiota (exposure)	Method	nSNPs	Beta	SE	p-value	OR	95%CI
EFMR (main)	Eubacteriumeligens group	IVW	8	−0.004	0.002	0.037	0.996	0.993–1.000
	RuminococcaceaeUCG011	IVW	8	0.002	0.001	0.046	1.002	1.000–1.003
	DefluviitaleaceaeUCG011	IVW	10	0.002	0.001	0.027	1.002	1.000–1.004
	Escherichia/Shigella	IVW	15	0.004	0.001	0.0003	1.004	1.002–1.006
	Haemophilus	IVW	10	−0.004	0.001	0.004	0.996	0.994–0.999
	Phascolarctobacterium	IVW	12	−0.002	0.001	0.048	0.998	0.996–1.000
	Lachnospira	IVW	7	0.004	0.002	0.023	1.004	1.001–1.008
	Catenibacterium	IVW	5	−0.002	0.001	0.045	0.998	0.996–1.000
	Anaerotruncus	IVW	12	0.004	0.001	0.010	1.004	1.001–1.007
	Blautia	IVW	11	−0.003	0.002	0.038	0.997	0.994–1.000
	Marvinbryantia	IVW	10	0.003	0.001	0.026	1.003	1.000–1.005