Table 2.
Proportions of the primary endpoint, remission, nephrotic status, and chronic renal failure development
| Numbers in analysis set | Achieved number | Proportion (%) | 95% confidence interval [%] | |
|---|---|---|---|---|
| (Primary endpoint) 50% reduction of the Up/Uc at Day 169 | 6 | 5 | 83.3 | [43.6, 97.0] |
| (1) More than 50% reduction of the Up/Uc and the Up/Uc is 0.2 to 2.0 g/gCr at Day 169 | 6 | 2 | 33.3 | [9.7, 70.0] |
| (2) Complete remission at Day 169 | 6 | 2 | 33.3 | [9.7, 70.0] |
| (3) Incomplete remission at Day 169 | 6 | 2 | 33.3 | [9.7, 70.0] |
| (4) Either incomplete or complete remission at Day 169 | 6 | 4 | 66.7 | [30.0, 90.3] |
| (5) Nephrotic status at Day 169 | 6 | 2 | 33.3 | [9.7, 70.0] |
| (6) Chronic renal failure development during the treatment period | 6 | 0 | 0.0 | [0.0, 39.0] |
Up/Uc urinary protein creatinine ratio