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. 2023 Nov 27;28(4):337–348. doi: 10.1007/s10157-023-02431-0

Table 2.

Proportions of the primary endpoint, remission, nephrotic status, and chronic renal failure development

Numbers in analysis set Achieved number Proportion (%) 95% confidence interval [%]
(Primary endpoint) 50% reduction of the Up/Uc at Day 169 6 5 83.3 [43.6, 97.0]
(1) More than 50% reduction of the Up/Uc and the Up/Uc is 0.2 to 2.0 g/gCr at Day 169 6 2 33.3 [9.7, 70.0]
(2) Complete remission at Day 169 6 2 33.3 [9.7, 70.0]
(3) Incomplete remission at Day 169 6 2 33.3 [9.7, 70.0]
(4) Either incomplete or complete remission at Day 169 6 4 66.7 [30.0, 90.3]
(5) Nephrotic status at Day 169 6 2 33.3 [9.7, 70.0]
(6) Chronic renal failure development during the treatment period 6 0 0.0 [0.0, 39.0]

Up/Uc urinary protein creatinine ratio