Fig.1.

A timeline during the hospital stay displays Galactomannan (Aspergillus-Ag) levels indicating the extent of the fungal infection, and neutrophil granulocytes count (Neutr. Gran. in Gpt/l = gigaparticle per liter) reflecting immune recovery. Alongside neutrophil levels, select lung CT-Scan images highlight fungal progression and pneumothorax. The chart also illustrates the administration of glucocorticoids, depicted in terms of cortisol-equivalency or anti-inflammatory potency, with 400 being the therapeutic threshold for IRIS, and the administration of intra venous Immunoglobulin G and three antimycotic treatments targeting Aspergillus flavus. For the voriconazole dosage regimen, it is given in milligrams and administered twice daily, with therapeutic drug monitoring for serum levels. Isavuconazole is administered at 200 mg/day, and Amphotericin at 250 mg/day, both at consistent dosages