TABLE 2.
Chow (n = 10) | HFpEF (n = 20) | |
---|---|---|
5 week diet | ||
HR (bpm) | 504.13 ± 24.11 | 485.66.52 ± 19.19 |
LVID,d (mm) | 3.40 ± 0.15 | 3.87 ± 0.07** |
LVID,s (mm) | 2.34 ± 0.13 | 2.83 ± 0.08** |
LVAW,d (mm) | 1.00 ± 0.09 | 1.07 ± 0.04 |
LVPW,d (mm) | 0.92 ± 0.06 | 0.96 ± 0.04 |
LV Mass (mg) | 139.88 ± 16.97 | 156.03 ± 5.56 |
LVFS (%) | 31.23 ± 1.73 | 28.14 ± 0.86 |
LVEF (%) | 59.67 ± 2.48 | 55.77 ± 1.45 |
Peak mitral E velocity (mm/s) | 645.82 ± 37.99 | 724.91 ± 19.79 |
Peak mitral A velocity (mm/s) | 362.16 ± 20.66 | 333.25 ± 12.72 |
Mitral E/A | 1.47 ± 0.03 | 2.22 ± 0.07**** |
Note: Data are expressed as the means ± SEM. **p < 0.01, ****p < 0.0001.
Abbreviations: A, peak Doppler blood inflow velocity across mitral valve during late diastole; E, peak Doppler blood inflow velocity across mitral valve during early diastole; HR, heart rate; LVID,d, left ventricular internal diastolic diameter; LVID,s, left ventricular internal systolic diameter; LVAW,d, left ventricular end‐diastolic anterior wall thickness; LVPW,d, left ventricular end‐diastolic posterior wall; LVFS, left ventricular fractional shortening; LVEF, left ventricular ejection fraction.