Table 4.
The 20 most-cited organoid articles ranked in order of the number of citations received.
| Rank | Article | Topics | No. of citations | Citations over year |
Author (first) | Journal | ||
|---|---|---|---|---|---|---|---|---|
| P1 | P2 | P3 | ||||||
| 1 | Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche | Disease modeling | 4,411 | 17 | 870 | 3,518 | Sato, Toshiro | Nature |
| 2 | Cerebral organoids model human brain development and microcephaly | Disease modeling | 2,920 | 0 | 257 | 2,654 | Lancaster, Madeline A. | Nature |
| 3 | Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium | Disease modeling | 2,308 | 0 | 240 | 2,058 | Sato, Toshiro | Gastroenterology |
| 4 | Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts | Disease modeling | 1,761 | 0 | 566 | 1,194 | Sato, Toshiro | Nature |
| 5 | Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2 | Basic research | 1,461 | 0 | 0 | 1,461 | Monteil, Vanessa | Cell |
| 6 | Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients | Biobanking | 1,432 | 0 | 24 | 1,406 | Van de Wetering, Marc | Cell |
| 7 | Organoid Models of Human and Mouse Ductal Pancreatic Cancer | Disease modeling | 1,307 | 0 | 36 | 1,268 | Boj, Sylvia F. | Cell |
| 8 | Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer | Basic research | 1,299 | 0 | 0 | 1,294 | Ohlund, Daniel | Journal of Experimental Medicine |
| 9 | Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro | Disease modeling | 1,299 | 0 | 273 | 1,022 | Spence, Jason R. | Nature |
| 10 | Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure | Disease modeling | 1,296 | 0 | 0 | 1,294 | Qian, Xuyu | Cell |
| 11 | Lgr5(+ve) Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro | Disease modeling | 1,115 | 0 | 354 | 759 | Barker, Nick | Cell Stem Cell |
| 12 | SARS-CoV-2 productively infects human gut enterocytes | Basic research | 1,068 | 0 | 0 | 1,067 | Lamers, Mart M. | Science |
| 13 | In vitro expansion of single Lgr5(+) liver stem cells induced by Wnt-driven regeneration | Precision medicine | 1,019 | 0 | 177 | 842 | Huch, Meritxell | Nature |
| 14 | Patient-derived organoids model treatment response of metastatic gastrointestinal cancers | Precision medicine | 1,004 | 0 | 0 | 1,000 | Vlachogiannis, Georgios | Science |
| 15 | Organoid Cultures Derived from Patients with Advanced Prostate Cancer | Disease modeling | 993 | 0 | 43 | 948 | Gao, Dong | Cell |
| 16 | Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver | Disease modeling | 973 | 0 | 33 | 937 | Huch, Meritxell | Cell Science |
| 17 | A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity | Biobanking | 971 | 0 | 0 | 967 | Sachs, Norman | Cell |
| 18 | Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway | Basic research | 968 | 0 | 0 | 963 | Viswanathan, Vasanthi S. | Nature |
| 19 | Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients | Basic research | 943 | 0 | 140 | 803 | Schwank, Gerald | Cell Stem Cell |
| 20 | Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis | Disease modeling | 929 | 0 | 2 | 925 | Takasato, Minoru | Nature |
P1, period 1: 2003 to 2009; P2, period 2: 2010 to 2015; P3, period 3: 2016 to 2023.