Table 3.
ΔbvgR in non-modulating (Bvg+) conditions.
| Cluster | ΔbvgR vs. WT Non-Mod | WT Non_Mod vs. Mod | ΔbvgR Non-mod vs. Mod | Description | Gene |
|---|---|---|---|---|---|
| a | Up | Down | Down | Vrgs repressed by BvgR in non-modulating (Bvg+) conditions and do not require BvgR for modulation | flaA (flagellar protein) |
| b | Up | Down | NS | Vrgs repressed by BvgR in non-modulating (Bvg+) conditions and require BvgR for modulation. | wcbA (capsular polysaccharide) |
| c | Down | Up | Up | Vags that require BvgR for full expression in non-modulating (Bvg+) conditions | PRN |
| d | NS | Down | Down | Vrgs not regulated by BvgR in non-modulating (Bvg+) conditions | ureE (urease) |
| e | NS | Up | Up | Vags not regulated by BvgR in non-modulating (Bvg+) conditions | FHA |
Transcriptional response of genes within clusters identified from comparisons used to evaluate the differential expression of the ΔbvgR mutant in non-modulating (Bvg+) conditions. Yellow, indicates genes upregulated (Up) (log2fc > 1); blue, indicates genes downregulated (Down) (log2fc < −1); white, no significant change or NS in gene expression (log2fc < 1, but > −1).