APS |
Astragalus polysaccharides |
Bcl-2 |
B-cell lymphoma-2 |
Bax |
Bcl-2-associated X |
HCC |
Hepatocellular cancer |
c-myc |
Myelocytomatosis viral oncogene homolog |
Cyclin D1 |
G1/S-Specific cyclin-D1 |
BC |
Breast cancer |
JNK |
c-Jun N-terminal kinases |
TNF |
Tumor necrosis factor |
JAK |
Janus kinase |
STAT |
Signal transducer of activators of transcription |
AKT |
Protein kinase B |
AMPK |
Adenosine monophosphate activated protein kinase |
BECN1 |
Beclin-1 |
GPX4 |
Glutathione peroxidase 4 |
xCT |
Light chain subunit SLC7A11 |
SIRT1 |
Silent mating type information regulation 2 homolog- 1 |
SREBP1 |
Recombinant Sterol Regulatory Element Binding Transcription Factor 1 |
SHP2 |
SH2 domain-containing protein tyrosine phosphatase 2 |
SOCS3 |
Suppressor of cy-tokine signaling proteins |
NF-κB |
Nuclear factor kappa-B |
EMT |
Epithelial-mesenchymal transition |
MIF |
Macrophage migration inhibitor factor |
PG2 |
APS for injection |
AXL |
Recombinant AXL Receptor Tyrosine Kinase |
NSCLC |
Non-small cell lung cancer |
VEGF |
Vascular endothelial growth factor |
EGFR |
Epidermal growth factor receptor |
HUVECs |
Human umbilical vein endothelial cells |
ROS |
Reactive oxygen species |
∆Ψm |
Mitochondrial membrane potential |
CDDP |
Cisplatin |
PD-L1 |
Programmed cell death protein-ligand 1 |
PI3K |
Phosphatidylinositol-3-kinase |
P-gp |
P-glycoprotein |
MMP |
Matrix metalloproteinase |
OGT |
O-GlcNAc transferase |
OGA |
O-GlcNAcase |
ERK |
Extracellular Regulated Protein Kinases |
IL |
Interleukin |
DC |
Dendritic Cells |
iNOS |
Inducible nitric oxide synthase |
NO |
Nitric oxide |
TNF |
Tumor necrosis facto |
MDSCs |
Myeloid-derived suppressor cells |
CD |
Cluster of Differentiation |
HIF-1 |
Hypoxia-inducible factor-1 |
MSN |
Moesin |
mTOR |
Mammalian rapamycin target protein |
P70S6K |
P70 ribosomal protein S6 kinase |
LC3B |
Microtubule-associated protein 1 light chain 3 Beta |
Beclin1 |
Bcl-2 interacting coiled-coil protein 1 |
ICI |
Immune checkpoint inhibitors |
Cyt-c |
Cytochrome c |
CIK |
Cytokine-induced killer cells |