Table 2. Primary Outcomes.
Diagnosis | Participants, No. | Proportion of participants positive for P-SYN, % (95% CI) | |
---|---|---|---|
P-SYN positivea | P-SYN negativeb | ||
Synucleinopathy | 213 | 10 | 95.5 (91.9-97.8) |
Parkinson disease | 89 | 7 | 92.7 (85.6-97.0) |
Multiple system atrophy | 54 | 1 | 98.2 (91.7-99.9) |
Dementia with Lewy bodies | 48 | 2 | 96.0 (86.3-99.5) |
Pure autonomic failure | 22 | 0 | 100 (84.6-100) |
No synucleinopathy | 4 | 116 | 3.3 (1.3-8.0) |
Abbreviation: P-SYN, phosphorylated α-synuclein.
Positive for P-SYN in at least 1 biopsy site.
Negative for P-SYN in all biopsy sites.