Table 3.

Data quality assessment of SACT^a administration and order records after the advanced HNC^b diagnosis^c.

SACT data quality checks			Data set A		Data set B
Task 1: patients with any SACT drug administration or order record after the advanced HNC diagnosis date, n (%)d			5592 (75.9)		4411 (38.7)
Task 2: SACT drug records with missing drug identity (name and code) information
	Value, n (%)	0 (0)		0 (0)
	Normalization of medication name	Normalized generic name		RxNorm ingredient level
Task 3: patients with target SACT administration date after the advanced HNC diagnosis date, 2015 onward, % (n/N)e			24.96 (1200/4808)		5.92 (237/4003)
Task 4: SACT drug administration records with complete administration date, n (%)			425,505 (100)		37,662 (100)
Task 5: gap (in d) between the target SACT drug administration dates, median (IQR; range)			21 (21-21; 1-113)		21 (11-21; 1-824)
Task 6: patients with target SACT order date after the advanced HNC diagnosis date			N/Af,g		N/Ag
Task 7 SACT drug order records with complete days supply and refill information, n (%)			1732 (53.4)		N/Ah
Task 8: SACT drug order records with complete order date, n (%)i			3241 (100)		8380 (100)
Task 9: distribution of gaps (in d) between target SACT drug order dates, normalized by days supply, refill, and cancelation record			N/Ag		N/Ag

^aSACT: systemic anticancer therapy.

^bHNC: head and neck cancer.

^cDrug administration refers to drugs administered by health care providers at the site of care, whereas drug order refers to prescriptions for drugs used at home.

^dTask 1 was applied to the full data sets, including 7366 and 11,386 patients in Data sets A and B, respectively.

^eTask 3 was applied for patients with the first advanced HNC diagnosis on or after January 1, 2015, including 4808 and 4003 patients in Data sets A and B, respectively.

^fN/A: not applicable.

^gTasks 6 and 9 were not conducted because they apply to an oral target SACT.

^hInformation about the number of refills, days supply, or alternative data elements was not available in Data set B.

ⁱThe total number of drug order records in Data set A (3241) and Data set B (8380) was used as the denominator in task 8.