Table 1.
Analysis of factors associated with intensive care unit-acquired weakness
|
Parameters
|
ICU-AW group (n = 370)
|
Non-ICU-AW group (n = 693)
|
χ
2/t/Z
|
P value
|
| Sex | 1.913 | 0.167 | ||
| Male, n (%) | 235 (63.51) | 410 (59.16) | ||
| Female, n (%) | 135 (36.49) | 283 (40.84) | ||
| Age in yr, mean ± SD | 65.29 ± 18.72 | 58.58 ± 18.75 | 31.013 | 0.000 |
| Sepsis, n (%) | 31 (8.38) | 31 (4.47) | 6.727 | 0.010 |
| Multiple organ dysfunction syndrome, n (%) | 96 (25.95) | 68 (9.81) | 50.307 | 0.000 |
| Hypoalbuminemia, n (%) | 275 (74.32) | 379 (54.69) | 67.286 | 0.000 |
| Acute cardiogenic failure, n (%) | 157 (42.43) | 205 (29.58) | 18.005 | 0.000 |
| Respiratory failure, n (%) | 231 (62.43) | 277 (39.97) | 83.798 | 0.000 |
| Acute kidney injury, n (%) | 63 (17.03) | 47 (6.78) | 27.956 | 0.000 |
| Anemia, n (%) | 191 (51.62) | 229 (33.04) | 35.942 | 0.000 |
| Diffuse intravascular coagulation, n (%) | 5 (1.35) | 8 (1.15) | 0.077 | 0.781 |
| Stress-related gastrointestinal bleeding, n (%) | 99 (26.76) | 74 (10.68) | 47.733 | 0.000 |
| Shock, n (%) | 224 (60.54) | 276 (39.83) | 43.152 | 0.000 |
| Hypertension, n (%) | 193 (52.16) | 263 (37.95) | 20.661 | 0.000 |
| Diabetes, n (%) | 83 (22.43) | 133 (19.19) | 1.564 | 0.211 |
| Coronary atherosclerotic heart disease, n (%) | 123 (33.24) | 132 (19.05) | 27.292 | 0.000 |
| Malignant tumor, n (%) | 81 (21.89) | 144 (20.78) | 0.179 | 0.673 |
| Rehabilitation therapy, n (%) | 20 (5.40) | 172 (24.82) | 93.687 | 0.000 |
| Mechanical ventilation duration in h, M (QL, QU) | 114 (9.75, 250) | 0 (0, 21) | 29.905 | 0.000 |
| Midazolam in mg, M (QL, QU) | 50 (0, 370) | 0 (0,20) | 127.872 | 0.000 |
| Norepinephrine in mg, M (QL, QU) | 20 (0, 120) | 0 (0, 16) | 81.127 | 0.000 |
| Length of intensive care unit stay in d, M (QL, QU) | 10 (6, 19) | 3 (1, 4) | 278.696 | 0.000 |
ICU-AW: Intensive care unit-acquired weakness.