Table 7.
Multiple linear regression analysis of serum AC, AC/FC, and clinical data A. Multiple linear regression analysis of serum AC, AC/FC, and clinical data.
|
A. Multiple linear regression analysis of serum AC, AC/FC, and clinical data | ||||
|---|---|---|---|---|
| Dependent variable: serum AC (log) | ||||
| Model 1 | Model 2 | Model 3 | Model 4 | |
| Independent variable | β-value (p-value) | β-value (p-value) | β-value (p-value) | β-value (p-value) |
| eGFR (log) | -0.267 (0.005)** | -0.280 (0.003)** | -0.267 (0.011)* | 0.258 (0.008)** |
| Hb | 0.002 (0.857) | -0.053 (0.643) | -0.082 (0.480) | -0.085 (0.468) |
| Alb | -0.021 (0.378) | 0.003 (0.976) | 0.043 (0.722) | 0.040 (0.741) |
| BNP (log) | 0.221 (0.029)* | 0.260 (0.012)* | 0.262 (0.011)* | 0.273 (0.011)* |
| Dependent variable: AC/FC (log) | ||||
| Model 1 | Model 2 | Model 3 | Model 4 | |
| Independent variable | β-value (p-value) | β-value (p-value) | β-value (p-value) | β-value (p-value) |
| eGFR (log) | -0.510 (<0.001)*** | -0.514 (<0.001)*** | -0.516 (<0.001)*** | -0.519 (<0.001)*** |
| Hb | -0.038( (0.696) | -0.056 (0.583) | -0.052 (0.619) | -0.051 (0.627) |
| Alb | -0.175 (0.086) | -0.167 (0.105) | -0.171 (0.113) | -0.171 (0.117) |
| BNP (log) | -0.009 (0.915) | 0.003 (0.551) | 0.003 (0.973) | 0.000 (0.996) |
| Model 1, unadjusted; Model 2, adjusted by age, Model 3, adjusted by age and sex, Model 4, adjusted by age, sex, and BMI. | ||||
|
B. Multiple linear regression analysis of eGFR, BNP and serum AC, AC/FC | |||
|---|---|---|---|
| Dependent variable: eGFR (log) | |||
| Model 1 | Model 2 | Model 3 | |
| Independent variable | β-value (p-value) | β-value (p-value) | β-value (p-value) |
| Serum AC (log) | 0.119 (0.173) | 0.114 (0.193) | 0.133 (0.133) |
| AC/FC (log) | -0.646 (<0.001)*** | -0.632 (<0.001)*** | -0.628 (<0.001)*** |
| Dependent variable: BNP (log) | |||
| Model 1 | Model 2 | Model 3 | |
| Independent variable | β-value (p-value) | β-value (p-value) | β-value (p-value) |
| Serum AC (log) | 0.248 (0.017)* | 0.263 (0.010)* | 0.262 (0.011)* |
| AC/FC (log) | 0.099 (0.334) | 0.047 (0.467) | 0.047 (0.645) |
Model 1, unadjusted; Model 2, adjusted for age, Model 3, adjusted for age and sex.
* p < 0.05, ** p < 0.01, *** p < 0.001. AC, acylcarnitine; AC/FC, the acylcarnitine/free carnitine ratio; eGFR, estimated glomerular filtration rate; Hb, hemoglobin; Alb, albumin; BNP, brain natriuretic peptide.