Table 3.
Incidence and adjusted hazard ratio of diabetes, hypertension, and both disorders by study cohort and Charlson comorbidity index score
| Disorder | Charlson comorbidity score | ||||||
|---|---|---|---|---|---|---|---|
| 0 | ≥ 1 | ||||||
| Events, N | Rate | HR (95% CI) | Events, n | Rate | HR (95% CI) | Interactions, p | |
| Diabetes | < 0.0001 | ||||||
| Comparison cohort | 5385 | 8.81 | Ref. | 1139 | 13.26 | 1.18 (1.11–1.26)*** | |
| Alcohol use disorder | 9290 | 18.32 | 2.07 (2.00–2.14)*** | 2403 | 33.14 | 3.23 (3.08–3.40)*** | |
| Hypertension | 0.0001 | ||||||
| Comparison cohort | 10,941 | 19.23 | Ref. | 2392 | 31.17 | 1.15 (1.10–1.21)*** | |
| Alcohol use disorder | 15,446 | 34.03 | 1.75 (1.71–1.80)*** | 2849 | 42.37 | 1.80 (1.73–1.88)*** | |
| Both | < 0.0001 | ||||||
| Comparison cohort | 3238 | 5.16 | Ref. | 617 | 6.91 | 1.04 (0.95–1.13) | |
| Alcohol use disorder | 5208 | 9.72 | 1.94 (1.86–2.03)*** | 1127 | 14.08 | 2.54 (2.37–2.72)*** | |
Notes: Rate, per 1000 person-years; HR, hazard ratio; CI, confidence interval
CI, confidence interval; HPA, health promotion administration; HR, hazard ratio; LHID, Longitudinal Health Insurance Database; WHO, World Health Organization