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. 2024 Mar 21;25:120. doi: 10.1186/s12859-024-05720-x

Table 3.

The predictive ability of four basic methods and ELPGV, and the comparison p-value between ELPGV and others in T1D, T2D, BD, RA, CAD, HT with WTCCC dataset

Method T1D T2D BD RA CAD HT
Predictive ability p-value Predictive ability p-value Predictive ability p-value Predictive ability p-value Predictive ability p-value Predictive ability p-value
ELPGV 0.8879 ± 0.0008 0.8471 ± 0.0009 0.9195 ± 0.0006 0.8843 ± 0.0008 0.8705 ± 0.0008 0.9132 ± 0.0006
BayesA 0.8664 ± 0.0009 9.037E−69 0.8022 ± 0.0014 9.330E−72 0.8984 ± 0.0007 5.191E−73 0.8628 ± 0.0010 1.454E−68 0.8459 ± 0.0010 6.011E−61 0.8879 ± 0.0007 2.525E−75
BayesB 0.8841 ± 0.0008 4.330E−27 0.8396 ± 0.0010 1.517E−33 0.9167 ± 0.0005 4.416E−32 0.8810 ± 0.0008 1.425E−27 0.8651 ± 0.0008 2.272E−28 0.9100 ± 0.0005 9.319E−29
BayesCπ 0.8863 ± 0.0008 1.827E−23 0.8447 ± 0.0010 6.458E−31 0.9168 ± 0.0006 9.400E−39 0.8827 ± 0.0008 9.640E−20 0.8688 ± 0.0008 1.720E−24 0.9111 ± 0.0006 9.426E−32
GBLUP 0.4957 ± 0.0030 1.597E−114 0.4390 ± 0.0032 1.090E−112 0.6311 ± 0.0023 2.207E−112 0.5337 ± 0.0025 4.853E−118 0.5459 ± 0.0028 7.565E−109 0.5596 ± 0.0028 3.421E−110

ELPGV is the ensemble learning based on BayesA, BayesB, BayesCπ and GBLUP

— Represents no explicit result was found in this method

type 1 diabetes (T1D), type 2 diabetes (T2D), bipolar disorder (BD), rheumatoid arthritis (RA), coronary artery disease (CAD) and hypertension (HT)