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. Author manuscript; available in PMC: 2024 Jun 1.
Published in final edited form as: Nat Photonics. 2023 Nov 16;17(12):1031–1041. doi: 10.1038/s41566-023-01299-6

Figure 2.

Figure 2.

Label-free optical coherence tomography (OCT) applications. a, Ophthalmic OCT of the human retina (cross-section) delineating individual retina layers. b, Computational adaptive optics to correct optical aberrations in the human eye to enable en face OCT of individual photoreceptors in the mosaic. Reproduced from Ref. 17. c, Fiber-optic catheter-based radial OCT of the human coronary artery to assess stent apposition, compared to intravascular ultrasound (greyscale image). Reproduced from Ref. 19. d, Intraoperative OCT for surgical oncology guidance. 3D images of human lymph nodes reveal increased scattering following metastatic involvement. Reproduced from Ref. 21. e, OCT of human skin, revealing architectural differences from atopic dermatitis. Adapted from Ref. 27. f, 3D OCT of mouse embryonic development, with real-time functional assessment of cardiac dynamics. Reproduced from Ref. 29.