Table 1. Frequency of primary and secondary glomerular diseases and their distribution among both adults and children.
|
Adults: n = 738 | Children: n = 302 | ||||||
|---|---|---|---|---|---|---|---|---|
| % of primary or secondary cases |
|
|
|
|
|
|
||
| Primary glomerular diseases | 828 (79.6) | n = 563 | 270 (48.0) | 293 (52.0) | n = 265 | 142 (53.6) | 123 (46.4) | |
| FSGS | 288 (27.7) | (34.8) | 212 (37.7) | 109 | 103 | 76 (28.7) | 48 | 28 |
| IgA nephropathy | 98 (9.4) | 11.8 | 88 (15.6) | 43 | 45 | 10 (3.8) | 3 | 7 |
| Postinfectious GN | 89 (8.6) | (10.7) | 24 (4.3) | 14 | 10 | 65 (24.5) | 31 | 34 |
| Membranous GN | 88 (8.5) | (10.6) | 79 (14.0) | 35 | 44 | 9 (3.4) | 3 | 6 |
| Minimal change disease | 88 (8.5) | (10.6) | 33 (5.9) | 18 | 15 | 55 (20.8) | 32 | 23 |
| Crescentic GN | 46 (4.4) | (5.6) | 38 (6.7) | 12 | 26 | 8 (3.0) | 4 | 4 |
| Mesangial proliferative* | 46 (4.4) | (5.6) | 28 (5.0) | 10 | 18 | 18 (6.8) | 10 | 8 |
| Endocapillary proliferative* | 41 (3.9) | (5.0) | 30 (5.3) | 22 | 8 | 11 (4.2) | 4 | 7 |
| Membranoproliferative | 34 (3.3) | (4.1) | 25 (4.4) | 7 | 18 | 9 (3.4) | 5 | 4 |
| Thin basement disease | 6 (0.6) | (0.7) | 4 (0.7) | 0 | 4 | 2 (0.8) | 1 | 1 |
| Others | 4 (0.4) | (0.5) | 2 (0.4) | 0 | 2 | 2 (0.8) | 1 | 1 |
| Secondary glomerular diseases | 212 (20.4) | n = 175 | 34 (19.4) | 141 (80.6) | n = 37 | 6 (16.2) | 31 (83.8) | |
| Lupus nephritis | 185 (17.8) | (87.2) | 159 (90.3) | 22 | 137 | 26 (70.3) | 1 | 25 |
| Henoch-Schönlein purpura | 7 (0.7) | (3.3) | 1 (0.6) | 0 | 1 | 6 (16.2) | 1 | 5 |
| Hemolytic-Uremic TMA | 7 (0.7) | (3.3) | 3 (1.7) | 3 | 0 | 4 (10.8) | 3 | 1 |
| Amyloidosis | 6 (0.6) | (2.8) | 6 (3.4) | 5 | 1 | 0 (0.0) | 0 | 0 |
| Diabetic nephropathy | 4 (0.4) | (1.9) | 4 (2.3) | 3 | 1 | 0 (0.0) | 0 | 0 |
| Anti-GBM disease | 2 (0.2) | (0.9) | 1 (0.6) | 0 | 1 | 1 (2.7) | 1 | 0 |
| Cryoglobulinemic GN | 1 (0.1) | (0.5) | 1 (0.6) | 1 | 0 | 0 (0.0) | 0 | 0 |
FSGS = focal and segmental glomerulosclerosis; GN = glomerulonephritis; TMA = thrombotic microangiopathy; M = male; F = female; IgA = immunoglobulin A; Anti-GBM = anti-glomerular basement membrane. *Not otherwise specified.