Table 2.

The summary of the current meta-analysis results.

Outcome or subgroup	No. of Studies	Participants	Statistical method	Effect size	P
Clinical effective rates	18	1333	RR (fixed), 95% CI	1.15 [1.10, 1.20]	<.00001*
			OR (fixed), 95% CI	3.20 [2.24, 4.57]	<.00001*
			RD (fixed), 95% CI	0.12 [0.09, 0.16]	<.00001*
YGTSS scores	12	854	SMD (random), 95% CI	−0.85 [−1.50, −0.19]	.01*
			MD (random), 95% CI	−2.42 [−3.97, −0.88]	.002*
TCM syndrome scores	8	566	SMD (random), 95% CI	−1.35 [−2.08, −0.63]	.0002*
			MD (random), 95% CI	−2.34 [−3.22, −1.45]	<.00001*
Adverse reaction	7	501	RR (fixed), 95% CI	0.26 [0.14, 0.49]	<.0001*
			OR (fixed), 95% CI	0.25 [0.13, 0.47]	<.0001*
			RD (fixed), 95% CI	−0.06 [−0.08, −0.03]	<.00001*

MD = mean difference, OR = odds ratio, RD = risk difference, RR = relative ratio, SMD = standardized mean difference, TCM = traditional Chinese medicine, YGTSS = Yale Global Tic Severity Scale.

^*Favors treatment group with statistical significance.