TABLE 1.
Validated examples of SecA2-dependent exported proteins of mycobacteria
| Protein | Signal peptide/transmembranea | Species | Function | Reference |
|---|---|---|---|---|
| Ms1704 | SP | M. smegmatis | SBP | 106 |
| Ms1712 | SP | M. smegmatis | SBP | 106 |
| PhoS1 (Rv0928) | SP | M. tuberculosis | SBP | 102 |
| DppA (Mmar_5154) | SP | M. marinum | SBP | 101 |
| Mce1A (Rv0169) | TM | M. tuberculosis | Mce transporter component | 102 |
| Mce1C (Rv0171) | SP | M. tuberculosis | Mce transporter component | 102 |
| Mce1E (Rv0173) | SP | M. tuberculosis | Mce transporter component | 102 |
| Mce1F (Rv0174) | TM | M. tuberculosis | Mce transporter component | 102 |
| SapM (Rv3310) | SP | M. tuberculosis | Phosphatase effector | 111 |
| PknG (Rv0410c) | None | M. tuberculosis M. marinum | Kinase effector | 101, 102 |
| LipO (Rv1426c) | SP | M. tuberculosis | Predicted esterase (possible effector) | 102 |
| SodA (Rv3846) | None | M. tuberculosis | Superoxide dismutase | 99, 293, 294 |
| KatG (Rv1908c) | None | M. tuberculosis | Catalase-peroxidase | 99 |
| LipA (Mmar_2284) | SP | M. marinum | Cell wall hydrolase | 99 |
| MMAR_3060 | SP | M. marinum | Conserved hypothetical | 101 |
a
SP, Signal peptide; TM, transmembrane.